monoblastic leukemia

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Thân thiện
Definition
  1. Noun:
    • A type of acute myeloid leukemia: "monoblastic leukemia" is a specific form of acute myeloid leukemia (AML) characterized by the uncontrolled proliferation of immature white blood cells called monoblasts and their more mature counterparts, monocytes, in the blood and bone marrow.
Usage
  • This term is used exclusively in medical and clinical contexts to diagnose and classify a specific subtype of blood cancer.
  • It is a highly technical term not used in everyday conversation.
Examples
  • Noun:
    • The patient's bone marrow biopsy confirmed a diagnosis of monoblastic leukemia.
    • Monoblastic leukemia is a rare but aggressive subtype of AML.
Advanced Usage
  • Classification: In medical literature, "monoblastic leukemia" is often classified under the FAB (French-American-British) classification system as AML-M5.
  • Clinical Context: The term is used when discussing cytomorphology, treatment protocols, and prognosis.
    • The treatment strategy for monoblastic leukemia may differ from other AML subtypes.
Variants and Related Words
  • Monoblastic (adj): Pertaining to or characterized by monoblasts.
    • The smear showed monoblastic cells.
  • Monocytic leukemia: A closely related term sometimes used interchangeably, though it may refer to a slightly more mature cell type.
  • Acute Monoblastic Leukemia (AMoL): A full synonym often used in medical coding and literature.
Synonyms
  • Acute monoblastic leukemia (AMoL)
  • AML-M5 (per the FAB classification)
Notes
  • This is a compound medical term. The core word "leukemia" refers to cancer of the blood-forming tissues. The modifier "monoblastic" specifies the particular cell type (monoblasts) that is proliferating abnormally.
Noun
  1. leukemia characterized by the proliferation of monocytes and monoblasts in the blood

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